Gastrohel (Vonoprazan 10mg)

Gastrohel (Vonoprazan 10mg) is a potassium-competitive acid blocker (P-CAB) used to reduce stomach acid. It is newer than traditional proton pump inhibitors (PPIs) and is known for its faster onset and longer-lasting acid suppression.


Main Uses of Gastrohel (Vonoprazan 10mg):

  1. Gastroesophageal Reflux Disease (GERD):

    • Treats acid reflux and heartburn symptoms.

    • Helps heal erosive esophagitis (inflammation of the esophagus).

  2. Helicobacter pylori (H. pylori) Eradication:

    • Used in combination therapy with antibiotics (like amoxicillin and clarithromycin) to eliminate H. pylori infection, which can lead to ulcers.

  3. Peptic Ulcer Disease:

    • Treats and prevents gastric and duodenal ulcers, especially those related to NSAID use.

  4. Zollinger–Ellison Syndrome (less commonly):

    • May be considered for treating excessive acid production due to tumors.


🔬 How It Works:

Unlike PPIs that block the H+/K+ ATPase enzyme irreversibly, Gastrohel (Vonoprazan 10mg) competitively blocks potassium binding on this enzyme, making it faster acting and more stable in the stomach’s acidic environment.