Helapride (Levosulpiride 25mg)
Helapride (Levosulpiride 25mg) is a prokinetic and antipsychotic drug, primarily used to treat gastrointestinal and psychiatric disorders. It belongs to the class of benzamides and acts by modulating dopamine receptors (primarily D2 receptors).
✅ Main Uses of Helapride (Levosulpiride 25mg):
🔹 Gastrointestinal Uses (most common):
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Functional Dyspepsia (Indigestion):
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Relieves bloating, fullness, nausea, and upper abdominal discomfort.
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Gastroesophageal Reflux Disease (GERD):
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Improves gastric motility and reduces acid reflux by enhancing stomach emptying.
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Irritable Bowel Syndrome (IBS):
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Especially useful in IBS with predominant bloating and upper GI symptoms.
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Gastroparesis:
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Helps treat delayed stomach emptying, often seen in diabetics.
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🔹 Psychiatric Uses:
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Depression with Somatic Symptoms:
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Occasionally used to manage mild depression, anxiety, or psychosomatic disorders.
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Schizophrenia (less common):
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As an antipsychotic, used in select cases, especially in low doses for negative symptoms.
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🧠 How It Works:
Helapride (Levosulpiride 25mg) blocks dopamine D2 receptors, mainly in the gut (to improve motility) and the brain (to affect mood and behavior).