Makzo (Esomeprazole 40mg)
Makzo (Esomeprazole 40 mg) is a proton pump inhibitor (PPI) that reduces the production of stomach acid. It is typically used in more severe or chronic cases of acid-related gastrointestinal disorders compared to the 20 mg dose.
✅ Uses of Makzo (Esomeprazole 40 mg)
🔥 1. Gastroesophageal Reflux Disease (GERD)
-
Healing erosive esophagitis (damage to the esophagus caused by stomach acid).
-
Relief from severe, persistent heartburn.
🩹 2. Peptic Ulcers (Gastric & Duodenal)
-
Especially when ulcers are:
-
H. pylori–associated (as part of combination therapy with antibiotics)
-
NSAID-induced ulcers, both treatment and prevention
-
🩺 3. Zollinger–Ellison Syndrome
-
A rare condition where the stomach produces excessive acid. Higher doses like 40 mg are required for effective control.
💊 4. Maintenance Therapy
-
Prevents relapse of acid-related conditions after healing, especially in patients with chronic or recurrent GERD or ulcers.
🛡️ 5. Stress Ulcer Prophylaxis (in hospitalized patients)
-
Sometimes used in patients at high risk of GI bleeding due to severe illness or multiple medications.
🔍 How It Works
-
Blocks the proton pump enzyme (H⁺/K⁺ ATPase) in stomach lining cells → reduces acid secretion.