{"id":2754,"date":"2025-05-04T06:18:19","date_gmt":"2025-05-04T06:18:19","guid":{"rendered":"https:\/\/helapharma.com\/?post_type=product&p=2754"},"modified":"2025-05-04T06:18:19","modified_gmt":"2025-05-04T06:18:19","slug":"sacubi-v-50-sacubitril-valsartan","status":"publish","type":"product","link":"https:\/\/helapharma.com\/?product=sacubi-v-50-sacubitril-valsartan","title":{"rendered":"Sacubi V 50 (Sacubitril + Valsartan)"},"content":{"rendered":"","protected":false},"excerpt":{"rendered":"

Sacubi V 50<\/strong> contains a lower-dose combination of Sacubitril + Valsartan<\/strong>, typically 24 mg Sacubitril + 26 mg Valsartan<\/strong>, and is used primarily in the management of heart failure with reduced ejection fraction (HFrEF)<\/strong>. This dose is often prescribed as a starting dose<\/strong> or for patients with low blood pressure<\/strong>, kidney impairment<\/strong>, or who are elderly and need careful dose titration.<\/p>\n

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\u2705 Uses of Sacubi V 50 (Sacubitril + Valsartan)<\/strong><\/h3>\n

\u2764\ufe0f 1. Heart Failure with Reduced Ejection Fraction (HFrEF)<\/strong><\/h4>\n
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    Improves symptoms like:<\/p>\n

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      Shortness of breath<\/p>\n<\/li>\n

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      Fatigue<\/p>\n<\/li>\n

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      Swelling (edema)<\/p>\n<\/li>\n<\/ul>\n<\/li>\n

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      Reduces risk of hospitalization and death<\/strong> due to heart failure.<\/p>\n<\/li>\n

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      Used in place of or after failure of ACE inhibitors or ARBs<\/strong>.<\/p>\n<\/li>\n<\/ul>\n

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      \ud83e\udde0 Mechanism of Action<\/strong><\/h3>\n
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        Sacubitril<\/strong>: Inhibits neprilysin<\/strong>, increasing levels of beneficial peptides that:<\/p>\n

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          Dilate blood vessels<\/p>\n<\/li>\n

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          Promote sodium excretion<\/p>\n<\/li>\n

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          Reduce heart strain<\/p>\n<\/li>\n<\/ul>\n<\/li>\n

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          Valsartan<\/strong>: Blocks angiotensin II receptors<\/strong>, preventing vasoconstriction and lowering blood pressure.<\/p>\n<\/li>\n<\/ul>\n

          Together, they:<\/p>\n

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            Improve heart efficiency<\/p>\n<\/li>\n

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            Lower afterload and preload<\/p>\n<\/li>\n

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            Delay disease progression<\/p>\n<\/li>\n<\/ul>\n","protected":false},"featured_media":2749,"template":"","meta":[],"product_brand":[],"product_cat":[114],"product_tag":[],"class_list":{"0":"post-2754","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-unimark-pharmaceuticals","8":"first","9":"instock","10":"shipping-taxable","11":"product-type-simple"},"_links":{"self":[{"href":"https:\/\/helapharma.com\/index.php?rest_route=\/wp\/v2\/product\/2754","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/helapharma.com\/index.php?rest_route=\/wp\/v2\/product"}],"about":[{"href":"https:\/\/helapharma.com\/index.php?rest_route=\/wp\/v2\/types\/product"}],"version-history":[{"count":1,"href":"https:\/\/helapharma.com\/index.php?rest_route=\/wp\/v2\/product\/2754\/revisions"}],"predecessor-version":[{"id":2755,"href":"https:\/\/helapharma.com\/index.php?rest_route=\/wp\/v2\/product\/2754\/revisions\/2755"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/helapharma.com\/index.php?rest_route=\/wp\/v2\/media\/2749"}],"wp:attachment":[{"href":"https:\/\/helapharma.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=2754"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/helapharma.com\/index.php?rest_route=%2Fwp%2Fv2%2Fproduct_brand&post=2754"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/helapharma.com\/index.php?rest_route=%2Fwp%2Fv2%2Fproduct_cat&post=2754"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/helapharma.com\/index.php?rest_route=%2Fwp%2Fv2%2Fproduct_tag&post=2754"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}